Search results for "methods [DNA Mutational Analysis]"

showing 10 items of 245 documents

THE ROLE OF NON-GAUSSIAN SOURCES IN THE TRANSIENT DYNAMICS OF LONG JOSEPHSON JUNCTIONS

2013

We analyze the effects of different non-Gaussian noise sources on the transient dynamics of an overdamped long Josephson junction. We find nonmonotonic behavior of the mean escape time as a function of the noise intensity and frequency of the external driving signal for all the noise sources investigated.

Josephson effectPhysicsFluctuation phenomena random processes noise and Brownian motionCondensed matter physicsGaussianJosephson devicesDynamics (mechanics)General Physics and AstronomyJosephson energyComputational methods in statistical physics and nonlinear dynamicSettore FIS/03 - Fisica Della MateriaPi Josephson junctionsymbols.namesakeRandom walks and Levy flightsymbolsTransient (oscillation)
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The Evolution of Territorial Occupation:

2012

International audience; The analysis of territorial changes over time raises many methodological questions. Despite a very frequent use of spatial analysis methods, few works underline their methodological shortcomings. This paper considers a comparison and discussion of exploratory statistical methods (notably Ripley's K function and its derivatives). It is worth noting three parameters in archaeological spatial analysis: scale, quality and quantity of input data. Archaeological data are intrinsically heterogeneous. Therefore, our approach proposes a multiscalar process integrating heterogeneous data. We describe a range of methods for the description and analysis of heterogeneous spatial …

K-function[SHS.STAT]Humanities and Social Sciences/Methods and statisticsPoint patternProcess (engineering)ESDASettlement changesArchaeologyRange (mathematics)GeographyRipley's K function[SHS.STAT] Humanities and Social Sciences/Methods and statisticsCommon spatial patternScale (map)[ SHS.STAT ] Humanities and Social Sciences/Methods and statisticsSpatial analysisAnalysis method
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Co-occurrence of resonant activation and noise-enhanced stability in a model of cancer growth in the presence of immune response.

2006

We investigate a stochastic version of a simple enzymatic reaction which follows the generic Michaelis-Menten kinetics. At sufficiently high concentrations of reacting species, the molecular fluctuations can be approximated as a realization of a Brownian dynamics for which the model reaction kinetics takes on the form of a stochastic differential equation. After eliminating a fast kinetics, the model can be rephrased into a form of a one-dimensional overdamped Langevin equation. We discuss physical aspects of environmental noises acting in such a reduced system, pointing out the possibility of coexistence of dynamical regimes where noise-enhanced stability and resonant activation phenomena …

KineticsNoise intensityComputational methods in statistical physics and nonlinear dynamicNoise (electronics)Stability (probability)Quantitative Biology::Cell BehaviorImmune systemNeoplasmsChemical kinetics and dynamics.AnimalsHumansImmunologic FactorsComputer SimulationStatistical physicsQuantitative Biology - Populations and EvolutionCell ProliferationFluctuation phenomena random processes noise and Brownian motionStochastic ProcessesModels StatisticalStochastic processChemistryChemical kinetics in biological systemPopulations and Evolution (q-bio.PE)Models ImmunologicalImmunity InnateLangevin equationFOS: Biological sciencesNeoplastic cellBiological systemSignal TransductionPhysical review. E, Statistical, nonlinear, and soft matter physics
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Early and midterm outcomes of bioresorbable vascular scaffolds for ostial coronary lesions: insights from the GHOST-EU registry.

2016

Aims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset, with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term, but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA), left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death, target vessel m…

LCX (29Target lesionMale52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostialp= 0.035)medicine.medical_treatmentMyocardial Infarction304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14Coronary Artery Disease030204 cardiovascular system & hematologyCoronary artery diseasebut their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA)0302 clinical medicineAbsorbable Implants030212 general & internal medicineMyocardial infarctionCircumflexRegistriesTissue Scaffolds32%)Drug-Eluting StentsMiddle AgedThrombosisCoronary VesselsAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA) left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death target vessel myocardial infarction or target lesion revascularisation. The database included a total of 1549 lesions in 1304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14; 16%) LCX (29; 32%) or LAD (47; 52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostial p= 0.618) post-dilation in 43% (versus 58% in the non-ostial group p= 0.008). At quantitative coronary angiography treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37] p= 0.035) but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groups respectively log-rank p= 0.005). The device-oriented composite endpoint occurred respectively in 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025 HR 2.65 [1.41-4.97]).OstiumAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subsetTreatment Outcomein 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025CardiologyFemale549 lesions in 1medicine.symptomCardiology and Cardiovascular MedicineAdultpost-dilation in 43% (versus 58% in the non-ostial groupmedicine.medical_specialtyor LAD (47HR 2.65 [1.41-4.97])but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groupsrespectivelyLesion03 medical and health sciencesPercutaneous Coronary Interventionwith higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long termleft anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular deathInternal medicinemedicineHumanstarget vessel myocardial infarction or target lesion revascularisation. The database included a total of 1Agedp= 0.008). At quantitative coronary angiographybusiness.industryPercutaneous coronary interventionp= 0.618)treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37]log-rank p= 0.005). The device-oriented composite endpoint occurredmedicine.diseaseSurgery16%)businessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Expertise et suivi d'une acquisition Lidar pour l'archéologie : l'exemple d'Autun

2014

National audience; Présentation de l'expertise mise en œuvre pour vérifier et valider une campagne d'acquisition de données LiDAR pour des objectifs archéologiques

LiDAR aéroporté[SHS.STAT]Humanities and Social Sciences/Methods and statistics[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistoryarchéologielaser aéroporté[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory[SHS.STAT] Humanities and Social Sciences/Methods and statistics[ SHS.STAT ] Humanities and Social Sciences/Methods and statistics
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Quelles synergies entre gestionnaires d'espaces protégés et scientifiques pour l'acquisition et la valorisation de données terrestres haute-résolutio…

2015

National audience; Le LIDAR est une technique de télédétection aéroportée permettant d'acquérir des images à haute résolution avec de multiples finalités, comme l'analyse des paysages anciens et l'évolution des paysages actuels. Très sensible et relativement coûteux, son usage requiert une importante technicité et expertise à toutes les étapes, de l'acquisition à la valorisation des données en passant par leur traitement. Cet exposé présente le partenariat impliquant gestionnaires, ingénieurs, et chercheurs mis en place entre le futur Parc national et la Maison des sciences de l'Homme de l'Université de Bourgogne, pour la réussite de l'opération.

Lidar[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory[SHS.STAT]Humanities and Social Sciences/Methods and statisticsparcs nationaux[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory[ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory[SHS.STAT] Humanities and Social Sciences/Methods and statisticspartenariat[SDE.ES] Environmental Sciences/Environmental and Society[SDE.ES]Environmental Sciences/Environmental and SocietyMSH[ SHS.STAT ] Humanities and Social Sciences/Methods and statistics[ SDE.ES ] Environmental Sciences/Environmental and Society
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Visualization of Jacques Lacan’s Registers of the Psychoanalytic Field, and Discovery of Metaphor and of Metonymy. Analytical Case Study of Edgar All…

2017

International audience; We start with a description of Lacan’s work that we then take into our analytics methodology. In a first investigation, a Lacan-motivated template of the Poe story is fitted to the data. A segmentation of the storyline is used in order to map out the diachrony. Based on this, it will be shown how synchronous aspects, potentially related to Lacanian registers, can be sought. This demonstrates the effectiveness of an approach based on a model template of the storyline narrative. In a second and more comprehensive investigation, we develop an approach for revealing, that is, uncovering, Lacanian register relationships. Objectives of this work include the wide and genera…

Linguistics and LanguageMetaphorComputer scienceGeometric Data Analysismedia_common.quotation_subjectlcsh:BF1-990[INFO.INFO-DS]Computer Science [cs]/Data Structures and Algorithms [cs.DS]BF[SHS.PSY]Humanities and Social Sciences/Psychology[INFO.INFO-DS] Computer Science [cs]/Data Structures and Algorithms [cs.DS]PScomputer.software_genre[INFO.INFO-CG]Computer Science [cs]/Computational Geometry [cs.CG][INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL][SHS.PSY] Humanities and Social Sciences/Psychology03 medical and health sciences0302 clinical medicineData visualization[SHS.STAT] Humanities and Social Sciences/Methods and statisticsNarrativePsychoanalytic theorymedia_commonGeometric data analysisPsychoanalysis and languageMetonymy[SHS.STAT]Humanities and Social Sciences/Methods and statisticslcsh:P101-410business.industryField (Bourdieu)Lacanian psychoanalysisCorrespondence Analysislcsh:Language. Linguistic theory. Comparative grammarLinguistics030227 psychiatryP1Psychiatry and Mental healthClinical PsychologyTopology Computationlcsh:Psychology[INFO.INFO-CG] Computer Science [cs]/Computational Geometry [cs.CG]Analytics[INFO.INFO-CL] Computer Science [cs]/Computation and Language [cs.CL]Artificial intelligencebusinesscomputer030217 neurology & neurosurgeryNatural language processing
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Analyse de l’évolution des formes de l’habitat dans la Plaine de Troyes du 5e millénaire à la fin de l’âge du Bronze

2015

International audience

Longue duréeHabitat[SHS.STAT]Humanities and Social Sciences/Methods and statistics[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryAge du Bronze[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory[SHS.GEO] Humanities and Social Sciences/Geography[SHS.STAT] Humanities and Social Sciences/Methods and statisticsNéolithique[SHS.GEO]Humanities and Social Sciences/GeographyTroyes AubeComputingMilieux_MISCELLANEOUS
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MULTI-SCALE ANALYSIS OF LUNG COMPUTED TOMOGRAPHY IMAGES

2007

A computer-aided detection (CAD) system for the identification of lung internal nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 project. The three modules of our lung CAD system, a segmentation algorithm for lung internal region identification, a multi-scale dot-enhancement filter for nodule candidate selection and a multi-scale neural technique for false positive finding reduction, are described. The results obtained on a dataset of low-dose and thin-slice CT scans are shown in terms of free response receiver operating characteristic (FROC) curves and discussed.

LungReceiver operating characteristicmedicine.diagnostic_testComputer sciencebusiness.industryFOS: Physical sciencesPattern recognitionComputed tomographyCADFilter (signal processing)Physics - Medical PhysicsScale analysis (statistics)Reduction (complexity)Computerized Tomography (CT) and Computed Radiography (CR ).medicine.anatomical_structuremedicineSegmentationMedical Physics (physics.med-ph)Artificial intelligencebusinessInstrumentationMedical-image reconstruction methods and algorithms computer-aided soMathematical Physics
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Finite-Time H∞ Filtering for T-S Fuzzy Discrete-Time Systems with Time-Varying Delay and Norm-Bounded Uncertainties

2015

In this paper, we investigate the filtering problem of discrete-time Takagi–Sugeno (T–S) fuzzy uncertain systems subject to time-varying delays. A reduced-order filter is designed. With the augmentation technique, a filtering error system with delayed states is obtained. In order to deal with time delays in system states, the filtering error system is first transformed into two interconnected subsystems. By using a two-term approximation for the time-varying delay, sufficient delay-dependent conditions of finite-time boundedness and $H_{\infty }$ performance of the filtering error system are derived with the Lyapunov function. Based on these conditions, the filter design methods are propose…

Lyapunov function0209 industrial biotechnology02 engineering and technologyFuzzy logicsymbols.namesake020901 industrial engineering & automationControl theoryArtificial Intelligence0202 electrical engineering electronic engineering information engineeringFiltering problemnorm-bounded uncertaintieslinear matrix inequalities (LMIs)T-S fuzzy systemMathematicsApplied MathematicsFilter (signal processing)Finite-time boundednesstime delayFilter designH-infinity methods in control theoryDiscrete time and continuous timeComputational Theory and MathematicsControl and Systems EngineeringBounded functionsymbols020201 artificial intelligence & image processingHâ filteringFinite-time boundedness; H∞ filtering; linear matrix inequalities (LMIs); norm-bounded uncertainties; T-S fuzzy system; time delay; Control and Systems Engineering; Computational Theory and Mathematics; Artificial Intelligence; Applied Mathematics
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